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DeCS
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Descriptor English:
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Complement Pathway, Mannose-Binding Lectin
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Descriptor Spanish:
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vía del complemento de lectina unida a manosa
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Descriptor Portuguese:
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Lectina de Ligação a Manose da Via do Complemento
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Synonyms English:
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Complement Pathway, Mannose Binding Lectin
Lectin Complement Pathway
Lectin Pathway, Mannan-Binding (Complement Activation)
Lectin Pathways, Mannan-Binding (Complement Activation)
Lectin-Complement Pathway
Lectin-Complement Pathways
Mannan Binding Lectin Complement Pathway
Mannan Binding Lectin Pathway (Complement Activation)
Mannan-Binding Lectin Complement Pathway
Mannan-Binding Lectin Pathway (Complement Activation)
Mannan-Binding Lectin Pathways (Complement Activation)
Mannose Binding Lectin Complement Pathway
Mannose-Binding Lectin Complement Pathway
Pathway, Lectin-Complement
Pathway, Mannan-Binding Lectin (Complement Activation)
Pathways, Lectin-Complement
Pathways, Mannan-Binding Lectin (Complement Activation)
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Tree Number:
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G12.274.849
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Definition English:
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Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX. |
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See Related English:
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Mannose-Binding Lectin
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History Note English:
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2003
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Allowable Qualifiers English:
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Record Number:
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37640
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Unique Identifier:
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D037582
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Occurrence in VHL:
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Similar:
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DeCS
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